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Polyradiculonévrite chronique idiopathique de l'enfant : évolution sous bolus de Méthylprednisolone
RAFAI M; MOUTAOUAKIL F; EL OTMANI H; FADEL H; BOULAAJAJ FZ; EL MOUTAWAKKIL B; GAM I; SLASSI I
REV NEUROL (Paris) , 2006, vol. 162, n° 6-7, p. 753-756 Doc n°: 126084 Localisation : Documentation IRR Descripteurs : AC242 - POLYRADICULONEVRITE GUILLAIN BARRE Chronic inflammatory demyelinating polyneuropathy (CIDP) in children is relatively rare and treatment is based primarily on intravenous immunoglobulins or oral corticosteroids. Boluses of methylprednisolone (MP) are a seldom used alternative. CASE REPORT: We report the case of an 8-year-old child, first presented at the age of 3 years, with recurring episodes of functional impotence of both lower limbs and walking impairment, partially reversible without treatment. Clinical, progressive, and electrophysiological data and the analysis of the cerebrospinal fluid were compatible with CIDP. MP boluses were administered: after a total eight monthly boluses, very satisfactory progression on the clinical and electrophysiological fronts was noted after 24 months. CONCLUSION: Childhood CIDP presents clinical, electrophysiological, progressive, and prognostic particularities, they recur readily and the outcome is good. Boluses of methylprednisolone are an alternative to the treatment of these neuropathies in childhood. Langue : FRANCAIS |
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