Article

In the last decade, a considerable number of articles has shown that exercise is
effective in improving motor performance in Parkinson disease. In particular,
recent studies have focused on the efficacy of intensive exercise in achieving
optimal results in the rehabilitation of patients with Parkinson disease. The
effects of intensive exercise in promoting cell proliferation and neuronal
differentiation in animal models are reported in a large cohort of studies, and
these neuroplastic effects are probably related to increased expression of a
variety of neurotrophic factors. The authors outline the relation between
intensive exercises and neuroplastic activity on animal models of Parkinson
disease and discuss the clinical results of different intensive strategies on
motor performance and disease progression in patients with Parkinson disease.

Langue : ANGLAIS