Article

Objective: To evaluate the effect of therapeutic ultrasound on the acute inflammation of soft-tissue injuries by measuring the levels of prostaglandin E-2 (PGE(2)) and leukotriene B-4 (LTB4). Design: Randomized. Case-control study. Setting: Laboratory animal facility. Animals: Thirty 3-month-old male Sprague-Dawley rats. Intervention: Rats with medial collateral ligament transection were given 5 minutes of pulsed ultrasound therapy (1:4) daily. With different durations (1, 5, 10d) and intensities (0, 0.5, 1.5, 2.3W/cm(2)). Main Outcome Measures: Levels of PGE(2) and LTB4. Results: The levels of PGE(2) and LTB4 were higher in all intensity subgroups that received 2.3W/cm(2) intensity on postinjury day 2. On postinjury day 11, LTB4 was significantly decreased. But PGE(2) was significantly increased. Conclusions: Pulsed ultrasound therapy may stimulate inflammation of acute ligament injury. (C) 2004 by the American Congress of Rehabilitation Medicine and the American Academy of Physical Medicine and Rehabilitation.

Langue : ANGLAIS