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Type A behavior and coronary atherosclerosis
SPARAGON B; FRIEDMAN M; BREALL WS
ATHEROSCLEROSIS , 2001, vol. 156, n° 1, p. 145-149 Doc n°: 101312 Localisation : Documentation IRR Descripteurs : FA331 - MALADIE CORONARIENNE Objectives: To evaluate whether the pathogenesis of type A behavior may involve the premature development of coronary atherosclerosis. Background: Type A or coronary-prone behavior is considered a possible risk factor for the development of coronary heart disease. Premature development of coronary atherosclerosis is suspected to play a role. Utilizing electron beam computed tomography, one can accurately determine the degree of coronary artery calcification, which is reflective of coronary atherosclerosis. Methods: We performed a study of 35 men who had no clinical evidence of coronary heart disease. Twenty exhibited severe type A behavior and 15 exhibited type B behavior. All subjects were given an Electron Beam Computed Tomography scan of their coronary arteries and a treadmill electrocardiogram. Results: Eight of the 20 (40%) type A subjects were found to have coronary calcification compared to none of the type B subjects (P=0.005). The correlation coefficient between type A score and coronary calcium score was 0.39 (P=0.09). Conclusions: The pathophysiology by which type A behavior increases the risk for coronary heart disease may involve the premature development of coronary atherosclerosis. Langue : ANGLAIS Tiré à part : OUI Identifiant basis : 2001217261 |
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