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Do general and multiple sclerosis specific quality of life instruments differ ?
MOORE F; WOLFSON C; ALEXANDROV L
CAN J NEUROL SCI , 2004, vol. 31, n° 1, p. 64-71 Doc n°: 111980 Localisation : Documentation IRR Descripteurs : AE - MOELLE, JF - QUALITE DE VIE Quality of life instruments provide information that traditional outcome measures used in studies of multiple sclerosis do not. It is unclear if longer, disease-specific instruments provide more useful information than shorter, more general instruments, or whether patients prefer one type to another. Methods: We conducted a cross-sectional study of quality of life in a multiple sclerosis clinic population using a mailed questionnaire that combined three different quality of life instruments; the SF-36, the Multiple Sclerosis Quality of Life Instrument-54, and the EuroQol EQ-5D. We assessed the feasability of using each instrument and patient preference for each, calculated correlation coefficients for the summary scores of each instrument and other measures of disease severity, and calculated odds ratios from proportional odds models comparing each instrument with the Expanded Disability Status Scale. Results: We did not find substantial differences between the three instruments. All were well-received by patients, and over 75% felt that the combination of the three instruments best assessed their quality of life. Langue : ANGLAIS Tiré à part : OUI |
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