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Importance of pre-clinical testing exemplified by femoral fractures in vitro with new bone preparation technique

KOLD S; BECHTOLD JE; MOUZIN O
CLIN BIOMECH , 2005, vol. 20, n° 1, p. 77-82
Doc n°: 117579
Localisation : Documentation IRR
Descripteurs : DE44 - TRAUMATISMES - CUISSE-FEMUR

A new bone preparation technique, using smooth tamps for bone compaction, has increased crucial initial implant stability. However, preparing the femur with bulky smooth tamps, which from size to size increases the same amount in anterior to posterior as in lateral to medial dimensions, has increased the risk of a femoral fracture. This study examined whether compaction also involved an increased femoral fracture risk when using newly developed smooth tamps with a slim anterior to posterior dimension. Methods. One femur in each pair of 10 cadaver femurs was prepared by the compaction technique using cylindrical reamers and smooth tamps. The contralateral femur was conventionally prepared with conical reamers and toothed rasps. The tamps and rasps differed in design as a proximal lateral tip was only present on the smooth tamps. Using a standardized test protocol, the instruments were driven into the femoral canal in controlled manner by a drop tower. Findings. At maximum test conditions, five of 10 femurs in the compaction group had fractured, as compared with no fractures in the rasping group. All fractures were longitudinal fissures in the greater trochanter, and these fissures were associated with the extended proximal lateral tip of the tamps. Interpretation. Since the lateral fractures in the compaction group were associated with the extended proximal lateral tip of the tamps, it seems that fracture rates are influenced by instrumentation design. Therefore adequate pre-clinical evaluation is warranted prior to the introduction of new implantation techniques. (C) 2004 Elsevier Ltd. All rights reserved.

Langue : ANGLAIS

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