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Metabolic development of necrotic bone in the femoral head following resurfacing arthroplasty. A clinical [18F]fluoride-PET study in 11 asymptomatic hips

ULLMARK G; SUNDGREN K; MILBRINK J; NILSSON O; SORENSEN J
ACTA ORTHOP , 2012, vol. 83, n° 1, p. 22-25
Doc n°: 158966
Localisation : en ligne

D.O.I. : http://dx.doi.org/DOI:10.3109/17453674.2011.641108
Descripteurs : DA536 - OSTEONECROSE

One concern regarding resurfacing arthroplasty is the
viability of the diminished femoral head and the postoperative risk of collapse,
or a femoral neck fracture. (18)F-fluoride positron emission tomography (F-PET)
enables us to assess bone viability despite there being a covering metal
component. By F-PET studies, we recently showed the absence of metabolism in the
remaining part of femoral heads, 1-4 years after surgery in 11 of 46 consecutive
cases. We now present the further development of bone metabolism in these 11
cases. METHODS: 10 patients (11 chips) with previously shown loss of
femoral head metabolism were evaluated by radiography and repeated F-PET scans,
3-6.5 years after surgery. The size of the area with low (18)F-fluoride PET
uptake in the femoral head was compared to that in earlier PET images. RESULTS:
No patients had any clinical symptoms; nor was any necrotic bone area visible in
plain radiographs. On F-PET scans, 2 patients showed a diminished area with low
uptake, 4 were unchanged, and 5 had enlarged areas. INTERPRETATION: Bone
metabolism surrounding a volume of bone with no metabolic activity changes
dynamically even 5 years after surgery. The presence of bone with minor uptake of
F-tracer, indicating low or no bone metabolism, with further progression in 5 of
11 cases leads us to conclude that resurfacing THA should be used restrictively.

Langue : ANGLAIS

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