Article

Fatigue in children and adolescents with multiple sclerosis (caMS) is
currently poorly understood.
This review aimed to provide greater insight into
this area and direction for future research by evaluating evidence of
associations between fatigue and clinical, psychological, and social factors in caMS. METHOD: Studies were identified by searching online databases,
hand-searching reference lists, and requesting unpublished literature from key
authors. Studies that examined fatigue in relation to at least one clinical,
psychological, or social factor in caMS were included. Data on design, sample
characteristics, measures of fatigue, clinical, psychological, and social
variables, and key findings were extracted. Twelve studies were narratively
synthesized. RESULTS: Clinical factors appeared largely unrelated to fatigue,
whereas associations between fatigue and tests of neurocognitive functioning, and
fatigue and diagnosable psychiatric disorders, were mixed. However, fatigue and
depressed mood consistently correlated. A small number of studies indicated
associations between fatigue and reduced quality of life and school performance.
INTERPRETATION: A sufficient explanatory model of fatigue in caMS is lacking as
studies in this area are few and diverse. Future research should endeavour to
identify potentially modifiable clinical and psychosocial factors that are
associated with fatigue in caMS so that interventions targeting such factors may
be developed.
CI - (c) 2015 Mac Keith Press.

Langue : ANGLAIS