Article

Studies were performed on 5 patients with idiopathic dystonia-parkinsonism symptoms with marked diurnal fluctuation. Levels of homovanillic acid and 5-hydroxyindoleacetic acid were not different from those in controls. Considerable improvement in dystonic movements and parkinsonian symptoms was obtained with a small dose of l-dopa, trihexyphenidyl hydrochloride, amantadine, or bromocriptine hydrochloride. Electrophysiological investigation confirmed that the dystonic movements, wich became remarkably worsened on attempted movement, contributed amportantly to the diurn diurnal fluctuation of symptoms.

Langue : ANGLAIS

Identifiant basis : 1985090003