Article

The objective of this study
was to determine the in vitro fertilization (IVF) outcome after testicular sperm
extraction (TESE) in a group of spinal cord injury (SCI) male patients not
compatible with conservative fertility treatment.Setting:University-affiliated
medical center.Methods:Thirty two SCI patients (C2 to L2) were referred to IVF
after repeated trials of electroejaculation (EEJ) or penile vibratory stimulation
(PVS), and full andrological evaluation. Testicular sperm aspiration (TESA) was
the method of choice for sperm extraction. Open TESE was performed only after a
negative TESA attempt. Clinical pregnancy and live birth rates were
determined.Results:A total of 106 testicular procedures were performed. Sperm was
found in 95 cycles (89.6%). The average metaphase II (MII) oocyte number was
11.0+/-4.2, an average of 5.1+/-2.3 oocytes became normally fertilized after
Intra Cytoplasmic Sperm Injection (ICSI) (fertilization rate 57.1%). On average,
2.7+/-1.2 embryos were replaced. The clinical pregnancy rate was 32/106 (30.2%)
per cycle and 19/32 (59.3%) per couple. Live birth rate was 62.5%
(20/32).Conclusions:TESA/E and IVF can provide excellent prognosis for SCI
patients that cannot be treated by EEJ or PVS.

Langue : ANGLAIS