Article

The aim of this study was to provide a comprehensive update on (1) the
overall prevalence of cerebral palsy (CP); (2) the prevalence of CP in relation
to birthweight ; and (3) the prevalence of CP in relation to gestational age.
METHOD: A systematic review and meta-analysis was conducted and reported, based
on the PRISMA (Preferred Reporting Items for Systematic Reviews and
Meta-analyses) statement. Population-based studies on the prevalence of CP in
children born in 1985 or after were selected. Statistical analysis was carried
out using computer package R, version 2.14. RESULTS:
A total of 49 studies were
selected for this review. The pooled overall prevalence of CP was 2.11 per 1000
live births (95% confidence interval [CI] 1.98-2.25). The prevalence of CP
stratified by gestational age group showed the highest pooled prevalence to be in
children weighing 1000 to 1499g at birth (59.18 per 1000 live births; 95% CI
53.06-66.01), although there was no significant difference on pairwise
meta-regression with children weighing less than 1000g. The prevalence of CP
expressed by gestational age was highest in children born before 28 weeks'
gestation (111.80 per 1000 live births; 95% CI 69.53-179.78; p<0.0327).
INTERPRETATION: The overall prevalence of CP has remained constant in recent
years despite increased survival of at-risk preterm infants.
CI - (c) The Authors. Developmental Medicine & Child Neurology (c) 2013 Mac Keith
Press.

Langue : ANGLAIS