Article

Chronic traumatic encephalopathy (CTE) has been linked to participation in
contact sports such as boxing and American football. CTE results in a progressive
decline of memory and cognition, as well as depression, suicidal behavior, poor
impulse control, aggressiveness, parkinsonism, and, eventually, dementia. In some
individuals, it is associated with motor neuron disease, referred to as chronic
traumatic encephalomyelopathy, which appears clinically similar to amyotrophic
lateral sclerosis. Results of neuropathologic research has shown that CTE may be
more common in former contact sports athletes than previously believed. It is
believed that repetitive brain trauma, with or possibly without symptomatic
concussion, is responsible for neurodegenerative changes highlighted by
accumulations of hyperphosphorylated tau and TDP-43 proteins. Given the millions
of youth, high school, collegiate, and professional athletes participating in
contact sports that involve repetitive brain trauma, as well as military
personnel exposed to repeated brain trauma from blast and other injuries in the
military, CTE represents an important public health issue. Focused and intensive
study of the risk factors and in vivo diagnosis of CTE will potentially allow for
methods to prevent and treat these diseases. Research also will provide policy
makers with the scientific knowledge to make appropriate guidelines regarding the
prevention and treatment of brain trauma in all levels of athletic involvement as
well as the military theater.
CI - Copyright (c) 2011 American Academy of Physical Medicine and Rehabilitation.
Published by Elsevier Inc. All rights reserved.

Langue : ANGLAIS