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Early intervention after perinatal stroke

BASU AP
DEV MED CHILD NEUROL , 2014, vol. 56, n° 6, p. 516-521
Doc n°: 170088
Localisation : Documentation IRR

D.O.I. : http://dx.doi.org/DOI:10.1111/dmcn.12407
Descripteurs : AL - NEUROREEDUCATION, AJ34 - ACCIDENT VASCULAIRE CEREBRAUX - NEUROLOGIE INFANTILE, AJ23 - PARALYSIE CEREBRALE

Perinatal stroke is the most common cause of hemiplegic cerebral palsy. No
standardized early intervention exists despite evidence for a critical time
window for activity-dependent plasticity to mould corticospinal tract development
in the first few years of life. Intervention during this unique period of
plasticity could mitigate the consequences of perinatal stroke to an extent not
possible with later intervention, by preserving the normal pattern of development
of descending motor pathways. This article outlines the broad range of approaches
currently under investigation. Despite significant progress in this area,
improved early detection and outcome prediction remain important goals.
CI - (c) 2014 Mac Keith Press.

Langue : ANGLAIS

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