Article

Slowing of information processing speed (IPS) is often considered
one of the primary deficits seen in multiple sclerosis (MS). IPS is usually
measured by tasks that involve many cognitive functions.
The aim of this study
was to determine whether similar IPS slowing can also be observed during two
simple, timed, psychomotor crossing-off tasks. METHOD:
The Crossing-Off Test
(COT), a simple psychomotor task, was performed under two conditions (COT1
corresponded to writing habits, COT2 used horizontal sweeping) in 25
relapsing-remitting MS patients (EDSS 0-1) and 25 healthy controls. RESULTS: The
MS group compared with the control group was impaired on COT1 (P=0.0043) and not
on COT2 (P=0.4), and the COT1 performance of MS patients with EDSS 1 was more
impaired than those of patients with EDSS 0 (P=0.008). DISCUSSION/CONCLUSION:
These results indicate that only some of the IPS cognitive subcomponents linked
with COT1 tasks are initially involved in the slowing of IPS during MS,
suggesting that different mechanisms are involved in each tested version of the
COT.
CI - Copyright (c) 2016 Elsevier Masson SAS. All rights reserved.

Langue : ANGLAIS