Article

OBJECTIVE: To examine the validity of the timed Up and Go (TUG) test as a measure
of functional mobility in persons with multiple sclerosis (MS) by using a
comprehensive framework based on construct validity (ie, convergent and divergent
validity). DESIGN: Cross-sectional study.
SETTING: Hospital setting.
PARTICIPANTS: Community-residing persons with MS (N=47). INTERVENTIONS: Not
applicable. MAIN OUTCOME MEASURES: Main outcome measures included the TUG test,
timed 25-foot walk test, 6-minute walk test, Multiple Sclerosis Walking Scale-12,
Late-Life Function and Disability Instrument, posturography evaluation,
Activities-specific Balance Confidence scale, Symbol Digits Modalities Test,
Expanded Disability Status Scale, and the number of steps taken per day. RESULTS:
The TUG test was strongly associated with other valid outcome measures of
ambulatory mobility (Spearman rank correlation, rs=.71-.90) and disability status
(rs=.80), moderately to strongly associated with balance confidence (rs=.66), and
weakly associated with postural control (ie, balance) (rs=.31). The TUG test was
moderately associated with cognitive processing speed (rs=.59), but not
associated with other nonambulatory measures (ie, Late-Life Function and
Disability Instrument-upper extremity function). CONCLUSIONS: Our findings
support the validity of the TUG test as a measure of functional mobility. This
warrants its inclusion in patients' assessment alongside other valid measures of
functional mobility in both clinical and research practice in persons with MS.
CI - Copyright (c) 2016 American Congress of Rehabilitation Medicine. Published by
Elsevier Inc. All rights reserved.

Langue : ANGLAIS