Article

OBJECTIVE: To evaluate the medium-term functional effect and the effect on
quality of life of a standardized rehabilitation program in patients with
inflammatory myopathies (IMs). DESIGN: A multicenter, randomized controlled
trial. SETTING: Four university hospitals. PARTICIPANTS: Patients (N=21) with
polymyositis. INTERVENTIONS: The intervention group participated in a 4-week
standardized, hospital-based rehabilitation program followed by a personalized,
self-managed, home-based rehabilitation program.
The control group received
physiotherapy on an outpatient basis. Study participants were evaluated at
inclusion, at the end of the rehabilitation program (1mo),
and then at 6 and 12
months. MAIN OUTCOME MEASURES: The primary efficacy criterion was the Health
Assessment Questionnaire Disability Index (HAQ-DI), and the secondary criteria
were quality of life (according to the Medical Outcomes Study 36-Item Short-Form
Health Survey [SF-36] questionnaire), muscle performance (isokinetic strength,
Motor Function Measure, and Kendall Manual Muscle Test), gait, pain, fatigue, and
biomarkers of tolerance and disease activity. RESULTS:
At 12 months, the mean +/-
SD HAQ-DI was significantly lower in the intervention group than in the control
group (.64+/-.53 vs 1.36+/-1.02; P=.026). The intervention group also had better
scores than the control group for some quality-of-life dimensions (SF-36 General
Health: 53.44+/-8.73 vs 36.57+/-22.10, respectively; P=.038; SF-36 Role Physical:
63.89+/-43.50 vs 17.86+/-37.40, respectively; P=.023)
and pain levels
(5.0+/-10.61 vs 33.38+/-35.68, respectively; P=.04) at 12 months. The program was
well tolerated by all the participants. CONCLUSIONS:
In patients with IMs, the
combination of a 4-week standardized rehabilitation program and a personalized,
home-based, self-managed rehabilitation program was well tolerated and had a
positive medium-term functional effect.
CI - Copyright (c) 2016 American Congress of Rehabilitation Medicine. Published by
Elsevier Inc. All rights reserved.

Langue : ANGLAIS