Article

Study participants were 50 consecutive patients undergoing elective open heart surgery. There were 39 men and 11 women, with a mean age of 58 +or- 10years.VO2 owygen extraction and arterial lactate were measured 1, 4, 12 and 24 h postoperatively. VO2 oncreased significantly during the first 12 h and stabilized thereafter. Oxygen extraction remained stable through the first 24 h. Covariance analysis on repeated measures showed that the extracorporeal circulatory period (P<0.01), age (P<0.01), body temperature (P<0.05) and use of noradrenalin (P<0.05) were predictive factors influencing postoperative VO2. Although arterial lactate increased significantly during the first 12h period, no correlation with VO2 was found. However, covariance analysis showed that female sex, patient age (older than 65 years) and bypass period were posotove correlating factors for the increase in arterial lactate.

Langue : ANGLAIS

Tiré à part : OUI

Identifiant basis : 2000213362