Article

OBJECTIVE: To determine bone mineral density (BMD) z scores in adults with
cerebral palsy (CP), an understudied population. DESIGN: Cross-sectional.
SETTING: Medical facility. PARTICIPANTS: Adults (N=48; mean age, 34.3+/-5.8y;
range, 25-46y) with CP. INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURES: BMD z scores at the lumbar spine and hip using dual-energy x-ray absorptiometry,
Gross Motor Function Classification System (GMFCS), body mass index (BMI), and
ambulatory status. RESULTS: Mean BMD z scores were -1.40 for the lumbar spine,
-1.36 for the total hip, and -1.02 for the femoral neck. The z scores were
significantly lower for the nonambulatory group at all 3 sites (P<.05).
Significant differences were found among GMFCS levels for the lumbar spine and
total hip z scores (P<.05). For the lumbar spine, the mean z scores for level V
(the lowest mobility level) were significantly lower than the mean for levels
I/II (P=.001), III (P=.002), and IV (P=.013). For the total hip, the mean z
scores for level V were significantly lower than the mean for levels I/II
(P=.045). A significant positive relationship between the z scores and age was
found for the lumbar spine (Spearman rho=.40, P=.005). Significant positive
relationships between BMI and z scores were found for all sites
(P<.05).
CONCLUSIONS: This study contributes to the sparse literature about bone health in
adults with CP. In contrast with pediatric data, z scores did not decrease as a
function of age in this adult cohort. This information is important for
clinicians considering treatment options for this population.
CI - Copyright (c) 2015 American Congress of Rehabilitation Medicine. Published by
Elsevier Inc. All rights reserved.

Langue : ANGLAIS