Article

PURPOSE: To identify the prognostic roles of initial glucose level in the
emergency department among patients with acute ischemic stroke, and to evaluate
whether or not the impact varied with diabetes. METHODS: A total of 774
first-ever ischemic stroke patients admitted to the emergency department of a
tertiary hospital in Taiwan. Participants were stratified into tertiles by
initial glucose level in the emergency department. The Barthel Index (BI) and
modified Rankin Scale (mRS) were used to assess functional outcome 3 months after
the ischemic stroke. RESULTS: Initial glucose level was significantly associated
with functional outcome 3 months after ischemic stroke. Compared with the 1st
tertile, adjusted odds ratios for 2nd and 3rd tertiles of initial glucose level
were 1.84 (95% confidence interval [CI], 1.15-2.95) and 4.57 (95% CI, 2.87-7.29),
for BI of less than 60, 2.07 (95% CI, 1.28-3.36) and 4.45 (95% CI, 2.76-7.18) for
mRS score of >2. The association was apparent among the nondiabetic stroke
patients compared with diabetic patients. CONCLUSIONS: A positive association was
found between initial glucose level and poor functional outcome at 3 months in
patients with acute ischemic stroke, particularly among nondiabetic patients.

Langue : ANGLAIS