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Membrane excitability and calcium homeostasis in exercising skeletal muscle
CARLSEN RC; VILLARIN JJ
AM J PHYS MED REHABIL , 2002, vol. 81, n° 11, p. S28-S39 Doc n°: 107375 Localisation : Documentation IRR Descripteurs : AB11 - NORMAL / ETUDES GENERALES / MUSCLES Preservation of the membrane electrochemical gradients for Na+, K+, and Ca2+ is vital to the maintenance of skeletal muscle structure and function. Muscle excitability may be depressed during contractile activity by changes in the gradients for Na+ and K+, while muscle force may be reduced by an activity-induced increase in free intracellular Ca2+ Compensatory processes help to maintain ion electrochemical gradients in normal, active muscles, but compensatory mechanisms may be impaired in Injured or diseased muscles contributing to muscle, pathology. Langue : ANGLAIS Identifiant basis : 2003225456 |
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