Article

This article aims to provide a comprehensive review of the current literature
that pertains to the therapeutic use of autologous platelet-rich plasma (PRP).
The basic science literature regarding the role of growth factors in mediating
the healing process and the laboratory data from in vitro and in vivo studies
that evaluated PRP are reviewed. Subsequently, the current evidence regarding PRP
efficacy from animal models, human surgical studies, and human clinical studies
is presented. A critical analysis of the literature follows, and the article
concludes with the authors' perspectives on the state of PRP as a potentially
efficacious bioregenerative treatment option for musculoskeletal and sports
medicine applications. The relevant articles in this review were obtained via
PubMed literature searches for PRP publications that pertain to musculoskeletal
and sports medicine conditions. This article is not intended to be a formal
meta-analysis.
CI - Copyright (c) 2011 American Academy of Physical Medicine and Rehabilitation.
Published by Elsevier Inc. All rights reserved.

Langue : ANGLAIS